Auf einer Routine-Expedition der NASA verliert der Astronaut Spencer für kurze Zeit den Kontakt zur Basis. Monate später leidet er unter Verhaltensstörungen, die zuerst seiner schwangeren Frau auffallen. Der Zwischenfall im All bekommt plötzlich eine große Bedeutung für die Menschen.
Länge: 109 Minuten

They were the perfect all-American couple - a courageous, honored NASA astronaut (Johnny Depp) and his beautiful school-teacher wife (Charlize Theron). They were passionately in love, so connected they could sense each other even when he was floating in space and she was two hundred thousand miles below.

And in two minutes it all turned to inexplicable terror.

For two minutes, astronaut Spencer Armacost loses total consciousness while on a bold space shuttle mission, returning home just barely alive and a bewildered hero. The President, the nation and his friends celebrate his safe return, but to his wife Jillian something seems strangely amiss from the moment he returns to earth.

Though very much in love with her husband, Jillian cannot help but question what happened to him out there in the lonely vacuum of space and whether it has changed him - and their marriage -- in some profound way. Especially when she begins having strangely violent dreams; dark, paranoid thoughts; and the strangest sensation that her husband is not the lover, or the man, he used to be. Things only get worse when Spencer's partner in space, Alex Streck (Nick Cassavetes), and his wife Natalie (Donna Murphy) experience their own mysterious ends.

Turning from a NASA career to a lucrative rocket-designing job in the private sector, Spencer and Jillian move to a lavish new apartment in Manhattan. Soon after, Jillian finds out she is expecting - and in keeping with the increase of her new life, she is expecting twins. But something is not quite right with this dream pregnancy, either. As her pregnancy advances, Jillian descends into a nightmare. Is it just pre-partum hormonal craziness, or is there something terribly wrong with Jillian's husband and babies? Is she just paranoid or is there really a conspiracy between Spencer, her doctors and even her closest family and friends to keep her in the dark? And is it just an embittered former NASA employee's (Joe Morton) fantasy, or is she really carrying inside her the end of humanity as we know it?

The Astronaut's Wife is a haunting love story of psychological horror that rides the razor's edge between imaginary terrors and the heart-stopping real thing. The film stars Johnny Depp and Charlize Theron as a loving couple torn asunder in a moment of extraterrestrial mystery. A New Line Cinema presentation, the film is written and directed by Rand Ravich.